To transmit negative numbers over serial, you can use two's complement representation. Two's complement representation is a way to represent negative numbers in binary. To find the two's complement representation of a negative number, you can first find the absolute value of the number in binary. Then, you can invert all the bits and add 1 to the result.
For example, to find the two's complement representation of -5, you can first find the binary representation of 5, which is 101. Then, you can invert all the bits to get 010, and add 1 to get 011. The two's complement representation of -5 is therefore 011.
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